While Novak Djokovic is the bookies pick to win at Flushing Meadows, ahead of world No.1 Daniil Medvedev, Kyrgios feels there will be a first time winner at the major - which commences on August 29.
Via his Instagram stories, Kyrgios selected Spanish teen sensation Carlos Alcaraz to win his first Grand Slam at the US Open.
The 19-year-old has already reached a career-high ranking of No.4 at such a tender age after an extraordinary start to his tennis journey.
Alcaraz has won five career titles already - including four in 2022 - with triumphs two Masters 1000 events in Miami and Madrid.
The Spaniard hasn’t been able to maintain his winning form during five-set tennis at Grand Slam level as of yet, but has still produced quality results at the majors, reaching quarter-finals at the US Open (2021) and the French Open (2022).
Alcaraz - who is fourth in the line of betting to win the US Open - will be hoping to have built the fitness base to challenge across the two weeks at a Grand Slam, with his best tennis capable of beating any player in the world.
Kyrgios himself is fifth-favourite to claim his first major in New York after the best season of his career, which has seen the enigmatic Aussie reach the final of Wimbledon, win a title at Washington and make semi finals at Halle, Stuttgart and Houston.
Fifth seed Djokovic could still yet be a withdrawal for the US Open, while Alexander Zverev has recently pulled out with injury.
US Open men’s singles seeds
Daniil Medvedev
Rafael Nadal
Carlos Alcaraz
Stefanos Tsitsipas
Novak Djokovic
Casper Ruud
Félix Auger-Aliassime
Cameron Norrie
Hubert Hurkacz
Andrey Rublev
Taylor Fritz
Jannik Sinner
Pablo Carreño Busta
Matteo Berrettini
Diego Schwartzman
Marin Čilić
Roberto Bautista Agut
Grigor Dimitrov
Alex de Minaur
Denis Shapovalov
Dan Evans
Botic van de Zandschulp
Frances Tiafoe
Nick Kyrgios
Francisco Cerúndolo
Borna Ćorić
Lorenzo Musetti
Karen Khachanov
Holger Rune
Tommy Paul
Maxime Cressy
Nikoloz Basilashvili
